Treatment For Gastroparesis Symptoms In Clearwater, FL

Objective testing before any procedure, not after. About 30 minutes from Clearwater across the Courtney Campbell Causeway.

Treatment for gastroparesis symptoms starts by proving two things: that your stomach is actually emptying slowly, and that nothing else explains what you are feeling. That means a 4-hour gastric emptying study, an upper endoscopy, and testing for the reflux and motility problems that produce the same nausea, bloating, and early fullness. A procedure enters the conversation only after those answers are in hand. Gopal Grandhige, MD, FACS, is a fellowship-trained foregut surgeon at Tampa Bay Reflux Institute in South Tampa, and he performs endoscopic pyloromyotomy for patients whose testing supports it.

What changed in gastroparesis care in 2025 and 2026

Two developments should shape any conversation you have about treatment right now.

In September 2025, the American Gastroenterological Association published its first clinical practice guideline on managing gastroparesis, with 12 conditional recommendations covering diagnosis and treatment. It is more conservative than what many patients have been told. The guideline advises against 2-hour or shorter gastric emptying studies in favor of the full 4-hour protocol. It conditionally supports metoclopramide and erythromycin as pharmacologic options, and it issues recommendations against domperidone, prucalopride, aprepitant, nortriptyline, buspirone, and cannabidiol as first-line therapy. It also advises against the routine first-line use of endoscopic pyloromyotomy or gastric electrical stimulation, reserving both for patients whose symptoms persist after medical therapy, and against routine botulinum toxin injection in refractory patients. On surgical pyloromyotomy and pyloroplasty, the panel issued no recommendation at all and named these as areas where the evidence is thin.

Read that last part carefully, because it cuts against how procedures are often marketed. The same guideline also names a foregut surgeon as part of the team for refractory disease, which is where a practice like this one belongs in the sequence.

The second development is naronapride, the first genuinely new prokinetic to reach late-stage development in years. The Phase 2b MOVE-IT trial enrolled 328 adults with moderate-to-severe idiopathic or diabetic gastroparesis over 12 weeks. Results announced in May 2026 showed the 20 mg and 40 mg three-times-daily doses met the primary endpoint on the core symptom score, with improvement across nausea, early satiety, post-meal fullness, and upper abdominal pain. In June 2026 the sponsors moved into Phase 3 studies with a planned US filing. It is not approved and not available outside a trial. It matters because it changes the honest answer to “is anything new coming” from no to not yet.

Most people with these symptoms do not have gastroparesis

This is the part that gets skipped, and it is the reason so many patients spend years on the wrong treatment.

Confirmed gastroparesis is uncommon. The National Institute of Diabetes and Digestive and Kidney Diseases reports that about 10 men and about 40 women per 100,000 have gastroparesis, while symptoms resembling it occur in roughly 1 in 4 US adults. The symptom picture is common. The diagnosis is not.

Nausea, early fullness, bloating, regurgitation, and upper abdominal pain overlap with several conditions Dr. Grandhige treats and several he does not operate on at all. Reflux disease and a hiatal hernia can produce nearly the same complaints. So can achalasia, which is a motility disorder of the esophagus rather than the stomach and requires an entirely different operation. Esophageal hypersensitivity, functional dyspepsia, and rumination can mimic all of it and respond to none of it surgically. Silent reflux sits in the same overlap, often after years of ENT and allergy workups that came back clean.

gastroparesis

Medications matter here too. GLP-1 receptor agonists slow gastric emptying by design, and opioids, certain antidepressants, and some blood pressure and allergy medications do the same. Symptoms that appear after starting one of those drugs are a different problem from primary gastroparesis, and they are handled differently.

Dr. Grandhige is direct about the consequence: the patients he declines to operate on are often the most frustrated people who walk out of his office. They would be more frustrated after an operation that did not change anything. If GERD or another mechanism is driving your symptoms, that is what gets treated.

The four questions answered before any procedure is discussed

Every gastroparesis evaluation at this practice works through the same four questions in the same order.

1. Is the stomach actually emptying slowly? A 4-hour scintigraphic gastric emptying study, not a 2-hour version. Shorter studies miss delayed emptying and produce false reassurance.

2. Is something else producing these symptoms? Upper endoscopy to assess anatomy and complications. Reflux testing when the history suggests it. Esophageal manometry when swallowing is part of the picture, because an esophageal motility disorder treated as a stomach problem goes nowhere.

3. Which specific symptoms would a pylorus procedure realistically change? Dr. Grandhige tells patients before anything is scheduled which symptoms he expects to improve, which may improve partially, and which he does not expect to change. Patients want one diagnosis to explain everything. Bodies rarely cooperate.

4. Has medical therapy been given a fair trial? Dietary modification, glucose control where diabetes is involved, and an appropriate prokinetic or antiemetic trial come first. This is also what the 2025 AGA guideline sets out.

His own framing, which he repeats to nearly every patient: the operation is the last step, and the decision-making is the surgery.

Endoscopic pyloromyotomy: who it helps, and who it does not

Endoscopic pyloromyotomy, also called G-POEM or POP, is performed through the mouth with a flexible endoscope. A tunnel is created under the pyloric muscle, the muscle is divided, and the opening between stomach and small intestine widens. There are no external incisions. Dr. Grandhige is one of a small number of surgeons performing it in Tampa Bay.

It is not a cure. No treatment for gastroparesis is. The goal is to reduce symptom burden, and the candidates who do best are the ones whose testing points clearly at delayed emptying that has not responded to medical management.

Some patients are better served by something else entirely. Gastric electrical stimulation is a different tool aimed mainly at the nausea and vomiting subset, and it is available in Pinellas County without crossing the bay. Patients with severe weight loss or malnutrition may need nutritional support before any definitive procedure is safe to consider. Patients whose symptoms trace back to a mechanism other than delayed emptying get referred to the right specialist instead, through relationships Dr. Grandhige has built with local gastroenterologists, ENT physicians, pulmonologists, and allergists over 16 years in this market. The handoff is direct, not a note into a void.

The full range of procedural options, including pyloroplasty, venting and feeding access, and the rare cases where more is required, is covered on the practice’s main page on gastroparesis diagnosis and treatment. Gastroparesis can also develop after prior stomach surgery, including after a fundoplication performed elsewhere, and those cases are evaluated differently again.

How the schedule works when you are coming from Clearwater

Consultations are usually scheduled within 2 weeks, and always within 4 weeks.

Before your visit, send records to info@tampareflux.com. Dr. Grandhige personally reviews prior endoscopy and pathology reports, gastric emptying studies, pH and manometry results, imaging, and the notes from your gastroenterologist, ENT physician, or primary care doctor. He arrives at the consultation already knowing your history. Records that arrive through standard release requests are frequently delayed or incomplete, which is why patients who send their own get further faster.

If your testing is already complete, one visit is usually enough to confirm the diagnosis and discuss options. If testing is still needed, expect two visits roughly 4 weeks apart: the first to review records and plan the workup, the second to go through results and decide. From first consultation to procedure generally runs 4 to 8 weeks.

For patients coming from Pinellas County, the office arranges testing close to home wherever it can be done reliably, so you are not crossing the bay repeatedly for studies. The practice works with a small number of testing sites to keep turnaround and quality consistent.

Insurance authorization is handled entirely by the office and is always secured before anything is scheduled. Complex cases can take 4 to 6 weeks. Patients who call their own insurer to speed things along usually slow it down.

After your procedure, Dr. Grandhige’s physician assistant, who assists in every surgical case, is reachable during office hours and knows your specific anatomy and recovery course. Dr. Grandhige is reachable directly after hours.

Why the surgeon matters more than the procedure

Dr.Grandhige in a medical setting

Outcomes in foregut surgery are decided before the operation begins, in the diagnosis and the selection.

Dr. Grandhige completed a Bachelor of Science at Johns Hopkins University, medical school at the University of Michigan, and his general surgery residency at Yale New Haven Hospital, followed by two fellowships there, including foregut and minimally invasive surgery. He is board certified, a Fellow of the American College of Surgeons, a member of SAGES, and a founding member of the American Foregut Society. He has practiced in Tampa Bay since 2009 and founded Tampa Bay Reflux Institute in 2022, continuing the foregut-focused practice he started as Tampa Bay Reflux Center. His published procedure volumes include more than 600 fundoplications, more than 600 LINX procedures, and more than 200 TIF procedures. More detail on his training and background is available on the practice site.

All surgical cases are performed at a single hospital, HCA South Tampa, with the same operating room team and anesthesia group. His medical assistants have worked with him for over a decade. That consistency is deliberate: a surgeon rotating between four facilities with four different teams cannot deliver the same predictability.

Verify all of it independently. Board certification through the American Board of Surgery physician lookup and the American College of Surgeons directory. Licensure and any disciplinary history through the Florida Department of Health Medical Quality Assurance license search. Check any physician you are considering, including this one.

Getting to the office from Clearwater

Tampa Bay Reflux Institute is at 1315 South Howard Avenue, Suite 101, Tampa, FL 33606. Phone: 813.922.2920. Office hours are 9 AM to 6 PM, Monday through Friday.

From Clearwater, the drive is roughly 30 minutes outside peak traffic via the Courtney Campbell Causeway (SR 60), which drops you onto Kennedy Boulevard a few minutes from the office. The Howard Frankland and Gandy bridges are alternatives when SR 60 backs up. Morning appointments from Pinellas County are easier to make than afternoon ones.

The office is in a yellow brick building directly next to Sally O’Neill’s Pizza on South Howard. Parking is behind the restaurant. Patients also travel here from St. Petersburg, Brandon, Riverview, Westchase, and from Orlando, Sarasota, Naples, and Jacksonville for foregut-specific evaluation.

Frequently asked questions

No. Most patients arrive by referral from a gastroenterologist, ENT physician, pulmonologist, or primary care doctor, but you can contact the office directly. Bring or send your prior records either way.

Consultations are usually scheduled within 2 weeks and always within 4 weeks. If your testing is already complete, one visit is often enough to reach a plan.

Wherever a study can be performed reliably close to home, the office arranges it there. The practice works with a limited set of testing sites to keep quality and turnaround consistent, and coordinates so that you make as few trips as possible.

No. There is no cure for gastroparesis. The procedure is aimed at improving stomach emptying and reducing symptom burden in patients whose testing supports it, and the 2025 AGA guideline reserves it for patients whose symptoms persist after medical therapy rather than as a first step.

Yes, and often more so. Normal emptying with persistent nausea, fullness, and bloating points toward reflux, a hiatal hernia, an esophageal motility disorder, or a functional cause, each of which is treated differently. Knowing what it is not narrows things considerably.

The office handles the entire process on your behalf, submits the documentation, and communicates directly with your insurer. Authorization is always secured before a procedure is scheduled. Complex cases can take 4 to 6 weeks.

Prior endoscopy and pathology reports, any gastric emptying study, pH or manometry results, barium swallow or other imaging, office notes from other specialists, and a list of current and prior medications. Send them to info@tampareflux.com so they can be reviewed before you arrive. Older studies are still useful for showing how the disease has progressed.

That possibility is discussed before anything is scheduled. Dr. Grandhige states in advance which symptoms he expects to improve and which he does not, and if symptoms outside that set remain, the next step is usually a referral to the specialist who handles that mechanism.

Take the first step

Talk to a foregut specialist about your symptoms. If you have been managing gastroparesis symptoms with diet changes and medication and want to know what your testing actually shows, that is the conversation to have.

get help today

Contact Us for an Appointment

An endoscopy cannot tell you if you have reflux. It can only tell you if you have complications of GERD. 

If you are unhappy with your reflux symptoms, come in and we can discuss testing and treatments that can accurately diagnose your problem. 

#reflux #gerd #hiatalhernia #gastroparesis #linx

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CALL US AT 813-922-2920
www.tampareflux.com

If you have a hiatal hernia and fit one of these categories, you should know your options. 

Dr. Grandhige is an expert in his field and performs 200 of these surgeries a year.  He is the only surgeon in the Tampa Bay Area who offers all surgical options - LINX, Fundoplications, TIF and will be one of 20 surgeons in America introducing the latest procedure RefluxStop in 2026. 

We accept most insurances but will verify yours before you come in.  These procedures are considered medically necessary and covered by your insurance.  You can expect to pay your in-network deductibles and nothing else. 

#hiatalhernia #reflux #GERD #LINX #refluxstop

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What causes reflux ?

1.  Weak lower esophageal sphincter
2.  Hiatal hernia
3.  Flattening of the Angle of His
4.  Poor esophageal motility
5.  Gastroparesis (slow stomach)

NOT increased acid production

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Don’t let GERD get in the way of living your life.  Request your appointment with us today on the link below. 
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https://tampareflux.com/contact-us/

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Anyone can be victim to GERD and though weight loss can help reduce GERD symptoms. Many athletes with high impact workouts may continue to have these symptoms. This may be a symptom of a hiatal hernia or other issue. We are more then happy to assist you in finding your solution, just click the link below. 
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If you are tired of avoiding your favorite foods or taking daily medications, we can help. 

We are the Tampa experts in reflux !  With years of experience and thousands of patients treated successfully, we offer all FDA approved anti-reflux procedures. 

Call 813-922-2920 to schedule your appointment
All major insurances accepted.

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Not all patients need surgical intervention.  Many patients are living a heartburn free life with their PPIs. However 40% of patients taking PPIs are not getting the relief they need.  If you are one of those, you have options!  Come in and find out more. 
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