Gastroparesis Management In Clearwater, FL

If your stomach empties too slowly, the fix starts with finding out why, not with another prescription refill or a rush to a procedure. Dr. Gopal Grandhige is a foregut surgeon in South Tampa, about a 30 to 40 minute drive across the bay from Clearwater. He treats gastroparesis, but he tests first. Delayed emptying often travels with other problems that change the whole plan, and many patients arrive after years of being told their symptoms are “just gastroparesis” when objective testing shows reflux, a hiatal hernia, or an esophageal motility problem adding to it.

Who this evaluation is for, and why it works differently

Consider a specialist evaluation if you have ongoing nausea, vomiting hours after eating, early fullness, bloating, or unintentional weight loss, and medication has not settled it. Most gastroparesis care in the Clearwater and Tampa Bay area stops at confirming that your stomach empties slowly. Dr. Grandhige treats delayed emptying as one piece of a larger picture and looks for what else is driving your symptoms before recommending anything.

That matters because the treatments diverge fast. A hiatal hernia, esophageal motility disorders such as achalasia, and functional dyspepsia can all produce nausea, fullness, and upper abdominal discomfort that look like gastroparesis. Treat the stomach while missing a coexisting condition and you end up partly better and still frustrated. This is the difference between a workup that confirms one diagnosis and a workup that rules the others in or out.

What the 2025 AGA guideline changed about when to consider a procedure

The current national guideline says to try diet and medication before any procedure, and to hold pyloromyotomy and gastric electrical stimulation for people whose symptoms do not respond to medical treatment. The American Gastroenterological Association published its gastroparesis clinical practice guideline in September 2025 with twelve recommendations, and several are worth knowing before you sit down with any surgeon.

The guideline calls for a 4-hour gastric emptying study rather than a 2-hour version, because shorter tests miss cases and produce false results. It names metoclopramide and erythromycin as reasonable first-line medications, and notes metoclopramide is still the only drug FDA-approved for gastroparesis. It recommends against domperidone, prucalopride, aprepitant, nortriptyline, buspirone, and cannabidiol as first-line agents. And it advises against jumping to gastric per-oral endoscopic pyloromyotomy (G-POEM) or gastric electrical stimulation as an early step, reserving them for select patients whose symptoms resist medical therapy, decided through shared decision-making.

This lines up with how Dr. Grandhige already practices. He does not treat a procedure as the default, and he does not operate on a patient whose testing does not support it. If you have already been told a procedure is your next step, the guideline gives you a fair question to ask: has medical therapy actually failed, and does the testing point to the pylorus?

Diagnosis: testing that goes past a standard emptying study

Accurate diagnosis means measuring how your stomach empties and checking for the conditions that mimic or accompany gastroparesis, not confirming delayed emptying and stopping there. Gastroparesis is delayed stomach emptying with no physical blockage. The NIDDK gastroparesis overview covers the basic definition, causes, and symptoms, so this page focuses on what a specialist workup adds. For how this practice approaches gastroparesis overall, start there.

Dr. Grandhige’s workup can include a 4-hour gastric emptying study to measure how much food remains over time, upper endoscopy to rule out obstruction and check the pylorus and for a hiatal hernia, esophageal manometry to test how well the esophagus moves food, and pH impedance testing when reflux may be feeding the symptoms. In selected cases he uses EndoFLIP, a tool that measures the pylorus and esophagus during the procedure, to guide the decision.

Each test answers a different question. The emptying study tells you whether the stomach is slow. Endoscopy tells you whether something structural is in the way. Manometry tells you whether the esophagus itself is part of the problem. Skip a piece and you risk treating the wrong thing, which is the most common reason a gastroparesis treatment fails to help.

GLP-1 medications and slow stomach emptying are not the same as gastroparesis

If your symptoms started after beginning a GLP-1 medication like semaglutide or tirzepatide, the delayed emptying may be a drug effect rather than chronic gastroparesis, and that changes the plan. GLP-1 receptor agonists, sold as Ozempic, Wegovy, Mounjaro, and Zepbound, slow gastric emptying on purpose. That is part of how they work. In some people it produces nausea, early fullness, and vomiting that mimic gastroparesis.

The distinction is not academic. Drug-related delayed emptying often improves when the medication is adjusted or paused under a physician’s guidance, while true gastroparesis is a chronic condition that needs its own plan. A careful history of what you take and when the symptoms began, paired with objective testing, separates the two. This is exactly the kind of question a standard emptying study alone will not answer, and it is a good reason to get a full evaluation before committing to any long-term treatment.

The treatment ladder: diet and medication first, a procedure only when it fits

Most people with gastroparesis are managed without surgery. First-line care is dietary: smaller and more frequent meals, lower fat and lower fiber when symptoms flare, and liquid calories when solids are hard to keep down. Medication comes next, guided by the first-line options above. Much of this can be handled close to home in Clearwater. You do not need to cross the bay for diet changes and a prescription.

When medication and diet do not control symptoms, and testing confirms the pylorus is contributing, Dr. Grandhige performs endoscopic pyloromyotomy (G-POEM). It is done entirely through the mouth, with no external incisions, at HCA South Tampa Hospital, where he operates with the same team on every case. The procedure relaxes the muscle at the stomach outlet so food moves through more easily, and most patients go home the same day.

Two honest points. G-POEM is not a cure, and it does not help everyone. It is for carefully selected patients whose testing points to a pyloric problem. And not every patient with gastroparesis symptoms needs it at all. Some do better with a medication change or with treatment of a coexisting condition like GERD or a hiatal hernia. The work is figuring out which group you are in before a procedure, not after.

Getting evaluated from Clearwater

You can start from Clearwater with a phone call and by sending your records ahead, so the first visit is spent on answers instead of paperwork. Before you arrive, Dr. Grandhige personally reviews any prior testing you send: gastric emptying studies, endoscopy and pathology reports, manometry, imaging, and notes from your gastroenterologist or other physicians. Email records to info@tampareflux.com before the appointment.

Most patients are seen within two weeks, and always within four. If you already have complete testing, a plan can often be discussed at the first visit. If you need testing, a second visit about four weeks later reviews the results and settles the plan, which keeps decisions based on data. From first visit to treatment, that usually runs four to eight weeks.

For out-of-town patients, the office coordinates testing to cut down on trips. When a study can be done closer to your home, they arrange it there, so your visit to South Tampa stays focused. The office is at 1315 South Howard Avenue, Suite 101, in a yellow brick building next to Sally O’Neill’s Pizza, with parking behind the restaurant. From Clearwater, it is roughly a 30 to 40 minute drive across the bay.

You can read more about Dr. Grandhige’s training and background, including his work with overlapping conditions like silent reflux (LPR) that often accompany delayed emptying.

tampa bay reflux institute logo

About the surgeon

Gopal Grandhige, MD, is a board-certified general surgeon who has focused on foregut surgery in the Tampa Bay area since 2009. He completed his fellowship in Foregut Surgery and Minimally Invasive Surgery at Yale-New Haven Hospital, earned his medical degree at the University of Michigan, and completed his undergraduate degree in biology at Johns Hopkins University. He is a Founding Member of the American Foregut Society, a member of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES), and a Fellow of the American College of Surgeons. He has performed over 600 fundoplications, over 600 LINX procedures, and over 200 TIF procedures, holds privileges across several Tampa Bay hospitals, and performs his surgeries at HCA South Tampa Hospital.

Frequently asked questions

Gastroparesis is usually managed rather than cured. Diet, medication, and, in selected cases, a procedure can reduce symptoms, but the goal is control and better quality of life, not a permanent fix. Testing helps set realistic expectations from the start.

Most people do not. National guidance and this practice both put diet and medication first, and hold a procedure for patients whose symptoms resist medical treatment and whose testing shows the pylorus is contributing.

It is a procedure done through the mouth, with no external cuts, that relaxes the muscle at the stomach outlet so food empties more easily. It is performed at HCA South Tampa Hospital, usually as a same-day procedure, and it is not a cure.

Possibly. GLP-1 medications slow stomach emptying by design and can cause gastroparesis-like symptoms. If your symptoms started after beginning one, that history matters, and the delayed emptying may improve when the medication is adjusted under your doctor’s care.

Because reflux, a hiatal hernia, and esophageal motility disorders cause the same symptoms and often coexist with gastroparesis. Testing for them prevents treating one problem while missing another.

Most patients are seen within two weeks, and always within four. You can begin from Clearwater by sending records to info@tampareflux.com, and the office coordinates testing to limit trips across the bay.

Send prior endoscopy and pathology reports, gastric emptying study results, manometry, any imaging, a medication list, and notes from other physicians to info@tampareflux.com, so the visit focuses on your diagnosis and options.

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An endoscopy cannot tell you if you have reflux. It can only tell you if you have complications of GERD. 

If you are unhappy with your reflux symptoms, come in and we can discuss testing and treatments that can accurately diagnose your problem. 

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CALL US AT 813-922-2920
www.tampareflux.com

If you have a hiatal hernia and fit one of these categories, you should know your options. 

Dr. Grandhige is an expert in his field and performs 200 of these surgeries a year.  He is the only surgeon in the Tampa Bay Area who offers all surgical options - LINX, Fundoplications, TIF and will be one of 20 surgeons in America introducing the latest procedure RefluxStop in 2026. 

We accept most insurances but will verify yours before you come in.  These procedures are considered medically necessary and covered by your insurance.  You can expect to pay your in-network deductibles and nothing else. 

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What causes reflux ?

1.  Weak lower esophageal sphincter
2.  Hiatal hernia
3.  Flattening of the Angle of His
4.  Poor esophageal motility
5.  Gastroparesis (slow stomach)

NOT increased acid production

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If you are tired of avoiding your favorite foods or taking daily medications, we can help. 

We are the Tampa experts in reflux !  With years of experience and thousands of patients treated successfully, we offer all FDA approved anti-reflux procedures. 

Call 813-922-2920 to schedule your appointment
All major insurances accepted.

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Not all patients need surgical intervention.  Many patients are living a heartburn free life with their PPIs. However 40% of patients taking PPIs are not getting the relief they need.  If you are one of those, you have options!  Come in and find out more. 
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