What Actually Changed in Heartburn Treatment in 2026
Two things changed on the medication side, and one widely repeated claim about surgery is still not true yet.
A new drug class arrived. Vonoprazan, sold as Voquezna, is the first potassium-competitive acid blocker approved in the United States. The FDA approved it on November 1, 2023 for healing erosive esophagitis, then on July 18, 2024 for heartburn relief in non-erosive GERD, which is the larger group. It works differently from a PPI: it does not need acid to activate, it starts working faster, it lasts longer, and it is taken once daily with or without food. The FDA’s own review documentation covers the trial data behind the approval. Most Clearwater pages ranking for heartburn either skip this entirely or mention it in passing.
A second one is under review. Sebela Pharmaceuticals filed a New Drug Application for tegoprazan on January 9, 2026, based on the Phase 3 TRIUMpH program in more than 2,000 US patients. Tegoprazan outperformed lansoprazole for healing erosive esophagitis at 2 and 8 weeks and for maintaining that healing at 24 weeks, including in the most severe grades. It is not approved. Ask about it, but do not plan around it.
Now the correction. RefluxStop is not available in the United States. It carries a CE mark in Europe and has multi-year outcome data there, but it remains under FDA premarket approval review. Implantica submitted its final response to the FDA’s remaining questions on May 20, 2026, following six pre-approval inspections. Several pages in this market describe RefluxStop as arriving in 2026 and count it as a fourth available procedure. It is not one yet. Dr. Grandhige intends to offer it when the FDA approves it, and until that happens this practice performs three anti-reflux procedures, not four.
None of this changes the underlying point. A better acid blocker is still an acid blocker. It will not repair a hiatal hernia.
Silent Reflux: The Test Most Clearwater Patients Have Never Had
If your symptoms are chronic throat clearing, hoarseness, cough, postnasal drip, ear pressure or a lump-in-the-throat sensation, standard reflux testing can come back normal and still be the wrong test.
Standard pH studies measure reflux above the lower esophageal sphincter. Laryngopharyngeal reflux, or silent reflux, happens higher, above the upper esophageal sphincter, in tissue that is far more sensitive than the esophagus. The scale of that difference matters: the esophagus can tolerate 40 to 50 reflux episodes a day, while the larynx and pharynx can become symptomatic from one episode a day. A study that only looks at the lower level will miss it.
Dr. Grandhige uses a customized 24-hour dual-channel pH impedance probe placed through the nose in the office. It measures at both levels, above the lower sphincter and above the upper sphincter, and because it includes impedance it captures non-acid reflux as well. That matters because bile, pepsin and trypsin reach the throat too, and a pH-only study cannot see them.
The clinical consequence is direct. LPR patients are commonly quoted around a 50 percent chance that surgery helps. With dual-level testing identifying who is actually refluxing into the pharynx, Dr. Grandhige reports symptom improvement in the range of 80 percent in the patients he selects. Roughly 50 to 60 percent of LPR patients who test end up with findings that justify a procedure. The other 40 to 50 percent are told no, which is the point of the test.
Two things patients should know before starting. This testing is technically demanding and reimbursed poorly, which is why most centers do not offer it. And LPR does not resolve on the timeline patients expect. Typical heartburn often stops the night of surgery. Throat symptoms generally take 4 to 6 months to improve.
The Procedures, and the Six-Step Process Behind the Choice
There is no best reflux operation. There is a right operation for a specific anatomy and physiology, and in a meaningful number of cases the right answer is no operation. Dr. Grandhige’s framing to patients: the operation is the last step, the decision-making is the surgery.
Every case runs through the same six-step selection process.
- Prove reflux is present, using objective pH testing and correlation between reflux events and symptoms, and establish whether it is acid, non-acid or bile-related.
- Map the anatomy, including hernia size, esophageal length and the relationship between stomach, diaphragm and esophagus.
- Measure esophageal function with manometry. This step is the most commonly skipped and the most common source of dysphagia and regret.
- Match symptoms to physiology, and state clearly which symptoms should improve, which may improve partially and which are unlikely to change.
- Weigh patient priorities such as durability, medication elimination, reversibility and the ability to burp or vomit. Preference refines the choice; it never overrides anatomy.
- Choose the procedure, or choose observation and medical management.
What Can Go Wrong, and Who Gets Told No
Every anti-reflux procedure adds resistance at the gastroesophageal junction, and that resistance has a cost.
After a fundoplication, bloating and difficulty vomiting are the common complaints. Making it harder for acid to come up also makes it harder for air and food to come up. Whether that is temporary or permanent depends on the wrap type. After LINX, early swallowing difficulty is common and a small number of patients have longer-term dysphagia; recovery requires actively swallowing small bites hourly to keep the device working through the inflammatory phase. After TIF, some patients still need some acid suppression even when symptoms improve.
All three are functional operations. Like a joint replacement, they work well, they are subject to wear, and revision may be needed across a lifetime.
Some patients are told no, and it is a longer list than most practices publish. Untreated severe motility disorders. Reflux-like symptoms with no objective reflux on testing. Esophageal hypersensitivity, functional chest pain and rumination, all of which imitate reflux and none of which surgery improves. Obese patients seeking TIF. Dr. Grandhige is direct about the human cost of this: the patients he declines to operate on are often the unhappiest people leaving the office, and they would be far unhappier after an operation that did not fix anything.
The other honest limit is scope. Surgery corrects reflux. It does not correct every symptom you walked in with. Heartburn and regurgitation may resolve completely while throat symptoms improve partially and bloating persists from a separate mechanism. Dr. Grandhige states which symptoms he expects to improve, which may improve partially and which are unlikely to change, before anything is scheduled, and asks patients to give it six months before evaluating what remains.
Coming From Clearwater: Records, Timeline and Who Is Treating You
Plan on 30 to 45 minutes each way, and send your records before you come.
Email prior studies to info@tampareflux.com ahead of the appointment: endoscopy and pathology reports, any pH testing including Bravo or catheter studies, manometry results, barium swallow or other imaging, office notes from your gastroenterologist, ENT, pulmonologist or allergist, a current medication list, and a list of prior surgeries. Studies from years ago are still useful for showing progression. Signed record releases get sent immediately, but fax systems and incompatible electronic records mean releases alone frequently arrive late or incomplete. Patients who bring their own records get a definitive visit instead of a preliminary one.
Dr. Grandhige reviews everything personally before you arrive, including how other physicians have interpreted your symptoms.
The timeline is structured deliberately. New patients are usually seen within 2 weeks and always within 4. If your testing is already complete, one consultation is typically enough and surgery can often be scheduled about 4 weeks out. If testing is needed, the first visit covers education and test planning, a second visit about 4 weeks later reviews results and finalizes the plan, and the target from first visit to surgery is roughly 8 weeks. Insurance authorization is handled entirely by the office, can take 4 to 6 weeks, and is always secured before surgery is scheduled.

All surgery is performed at HCA South Tampa Hospital. Dr. Grandhige used to operate at four area hospitals and deliberately consolidated to one, so the same anesthesia team, nurses and surgical technologists handle every case. His own employed physician assistant assists every operation, knows each patient’s specific anatomy, and handles postoperative questions. After hours, patients reach Dr. Grandhige directly. Several of the medical assistants have worked with him for over a decade.
On credentials: Dr. Grandhige completed a bachelor of science in biology at Johns Hopkins University, his medical degree at the University of Michigan, general surgery residency at Yale New Haven Hospital, and two fellowships there, one in burn and critical care and one in foregut and minimally invasive surgery. He is a board-certified general surgeon, a Fellow of the American College of Surgeons, a member of SAGES, and a founding member of the American Foregut Society. He has practiced in Tampa Bay since 2009 and founded the practice profiled on our about us page in 2022. Verify his license and disciplinary history yourself through the Florida Department of Health MQA search portal.
The office is in a yellow brick building at 1315 South Howard Avenue, Suite 101, next to Sally O’Neill’s Pizza, with parking behind the restaurant.
Frequently Asked Questions
Get an Answer Instead of Another Prescription
The goal of the first visit is a clear answer: whether reflux is present, why it is happening, which of your symptoms it explains and which it does not. That holds whether the outcome is surgery, better medical management, or no intervention at all.
An endoscopy cannot tell you if you have reflux. It can only tell you if you have complications of GERD.
If you are unhappy with your reflux symptoms, come in and we can discuss testing and treatments that can accurately diagnose your problem.
#reflux #gerd #hiatalhernia #gastroparesis #linx
CALL US AT 813-922-2920
www.tampareflux.com
If you have a hiatal hernia and fit one of these categories, you should know your options.
Dr. Grandhige is an expert in his field and performs 200 of these surgeries a year. He is the only surgeon in the Tampa Bay Area who offers all surgical options - LINX, Fundoplications, TIF and will be one of 20 surgeons in America introducing the latest procedure RefluxStop in 2026.
We accept most insurances but will verify yours before you come in. These procedures are considered medically necessary and covered by your insurance. You can expect to pay your in-network deductibles and nothing else.
#hiatalhernia #reflux #GERD #LINX #refluxstop
What causes reflux ?
1. Weak lower esophageal sphincter
2. Hiatal hernia
3. Flattening of the Angle of His
4. Poor esophageal motility
5. Gastroparesis (slow stomach)
NOT increased acid production
Don’t let GERD get in the way of living your life. Request your appointment with us today on the link below.
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https://tampareflux.com/contact-us/
Anyone can be victim to GERD and though weight loss can help reduce GERD symptoms. Many athletes with high impact workouts may continue to have these symptoms. This may be a symptom of a hiatal hernia or other issue. We are more then happy to assist you in finding your solution, just click the link below.
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https://tampareflux.com/contact-us/
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#tampabayrefluxinstitute #guthealth #roboticsurgery
Heartburn may seem like an annoyance. But if you find yourself having symptoms on a daily basis, it may be time to to talk to Dr. Grandhige as it could be a symptom of something worse.
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#nonsurgicalweightloss #ESG #gastricballoon #weightlossjourney #vsg #vsgjourney #spatz3 #orbera #orberaballoon #grandhige #DrG
#tampabayrefluxinstitute #guthealth #roboticsurgery
If you are tired of avoiding your favorite foods or taking daily medications, we can help.
We are the Tampa experts in reflux ! With years of experience and thousands of patients treated successfully, we offer all FDA approved anti-reflux procedures.
Call 813-922-2920 to schedule your appointment
All major insurances accepted.
Not all patients need surgical intervention. Many patients are living a heartburn free life with their PPIs. However 40% of patients taking PPIs are not getting the relief they need. If you are one of those, you have options! Come in and find out more.
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#letushelpyou #medsnotworking #reflux #PPIs #heartburn #LINX #fundoplication #TIF #GERD#tampaheartburn #linx #TIF #fundoplication #tampabayreflux #GERD #acidreflux #acidrefluxsurgery #stopreflux
#nonsurgicalweightloss #ESG #gastricballoon #weightlossjourney #vsg #vsgjourney #spatz3 #orbera #orberaballoon #grandhige #DrG
#tampabayrefluxinstitute #guthealth #roboticsurgery
#heartburn #stopreflux #hiatalherniarepair #severeheartburn #reflux #tampabayreflux #acidrefluxsurgery #tampaheartburn #GERD #PPIs #achalasia #LINX #TIF #tampareflux #fundoplication #stomach #digestivehealth #ESG #obesity #overweight #weightlossjourney #gastricballoon
