Treating Gastroparesis In St. Petersburg, FL

Endoscopic pyloromyotomy and expert foregut evaluation with Dr. Gopal Grandhige, MD, FACS, a short drive across the bay in South Tampa.

Endoscopic pyloromyotomy for gastroparesis, a short drive from St. Petersburg

If gastroparesis medication and diet changes have stopped controlling your nausea, bloating, and early fullness, there’s a procedure most Tampa Bay practices don’t offer. Dr. Gopal Grandhige performs endoscopic pyloromyotomy, an operation done entirely through the mouth that loosens the pyloric muscle so the stomach empties more easily. He’s one of only a handful of surgeons in the Tampa Bay area who performs it.

His foregut practice is in South Tampa, a short drive across the bay from St. Petersburg. Patients come from St. Pete, across Pinellas County, and from all over Florida for a specialist who treats the esophagus, diaphragm, and stomach every day, not occasionally.

Gastroparesis is delayed gastric emptying, a disorder that slows or stops food moving from the stomach into the small intestine even though nothing is physically blocking it. It’s not rare in the way people assume. The NIDDK reports that about 10 in 100,000 men and 40 in 100,000 women have it, while symptoms that look like gastroparesis affect roughly 1 in 4 US adults. That overlap is part of why the condition gets misread as ordinary acid reflux or IBS for years.

One thing to know up front: not everyone with gastroparesis symptoms needs a procedure, and Dr. Grandhige will tell you plainly if you don’t. More on that below.

What endoscopic pyloromyotomy does

Endoscopic pyloromyotomy improves stomach emptying by cutting the pylorus, the ring of muscle between your stomach and small intestine, so food drains more freely into the intestine. Dr. Grandhige performs it with a flexible endoscope passed through the mouth. There are no incisions on your abdomen.

During the procedure, a small tunnel is made under the pyloric muscle with the endoscope, and the muscle is divided with an endoscopic knife. You may see it called POP (per-oral pyloromyotomy) or G-POEM. The two names describe minor technical variations of the same idea. Because everything is done internally, there are no abdominal wounds to heal.

This is increasingly used as an early procedural step for gastroparesis, not only as a last resort. It targets the mechanical bottleneck at the pylorus instead of just muting symptoms with medication. The practice’s main gastroparesis overview walks through the full treatment ladder in general terms; this page is written for patients coming from St. Petersburg.

Endoscope treating the pylorus valve to improve digestion flow.

Who is a candidate, and who isn’t

A procedure only makes sense once testing confirms your stomach is emptying too slowly and that the slow emptying is what’s actually causing your symptoms. That evidence comes from a gastric emptying study, the most useful test for gastroparesis. You eat a light meal tagged with a small amount of radioactive material, usually eggs and toast or oatmeal, and a scanner tracks how fast your stomach clears it over four hours.

An upper endoscopy doesn’t diagnose gastroparesis on its own, but it plays a role. If food is still sitting in your stomach after you’ve fasted for the test, that points toward delayed emptying and prompts a proper emptying study.

Here’s where Dr. Grandhige’s approach differs from a surgeon who operates on symptoms alone. He’s known across Tampa Bay for not operating unless the testing clearly supports it. Many patients arrive expecting a procedure and leave with a diagnosis, an explanation, and a non-surgical plan. Nausea, bloating, and fullness can also come from reflux, a hiatal hernia, silent reflux (LPR), or functional stomach disorders that a pyloromyotomy won’t fix. Confirming the cause first is what protects you from a procedure that can’t help you.

How gastroparesis treatments compare

Gastroparesis has no cure. Diet, medication, and procedures all aim at the same two things: fewer symptoms and steady nutrition. They’re usually tried in that order.

Diet comes first, and for many people it does real work. Smaller, more frequent meals, thoroughly chewed and well-cooked low-fat foods, and cutting out carbonation, alcohol, and smoking all reduce the load on a slow stomach. The practice can point you to a dietitian who works with gastroparesis, since staying nourished is the first priority.

Medication is the next step. Promotility drugs like metoclopramide (Reglan) and erythromycin speed the stomach up, though metoclopramide carries side-effect limits on long-term use and erythromycin tends to lose its effect over time. Domperidone has a gentler side-effect profile but is hard to get in the US. Separate anti-nausea medicines such as ondansetron (Zofran), prochlorperazine (Compazine), and diphenhydramine (Benadryl) manage the nausea and vomiting directly.

When diet and medication stop being enough, that’s when a procedure enters the picture. Endoscopic pyloromyotomy is Dr. Grandhige’s approach because it opens the pylorus without an incision and without an implant. Some centers instead use gastric electrical stimulation, an implanted device with a battery that needs replacing over the years, which the NIDDK notes is reserved for diabetic or unexplained gastroparesis when medication can’t control symptoms. A surgical pyloroplasty, done through small abdominal incisions, is another way to open the pylorus. Which one fits depends on your anatomy, your test results, and your history, not on which device a practice happens to sell.

Be clear-eyed about results. In this respect gastroparesis is handled much like achalasia, a related motility disorder: treatment eases the symptoms rather than curing the condition. A pyloromyotomy can improve emptying and cut symptoms, but it isn’t a reset button, and most patients still watch their diet afterward. Honest expectations are part of the plan here, not an afterthought.

Why see a foregut specialist for gastroparesis

Gastroparesis sits inside foregut surgery, the care of the esophagus, diaphragm, and stomach. Dr. Grandhige has worked in that one area since 2009. He’s a board-certified general surgeon who completed fellowship training in foregut and minimally invasive surgery at Yale-New Haven Hospital. He’s a Fellow of the American College of Surgeons, a member of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES), and a founding member of the American Foregut Society. You can read more about his training and background if you want to check the details yourself.

That focus shows up in volume. He’s performed over 600 fundoplications, over 600 LINX procedures, and over 200 TIF procedures for reflux, and he’s one of only a handful of surgeons in Tampa Bay who performs the endoscopic pyloromyotomy for gastroparesis.

The setup around the procedure matters as much as the credential. He operates at a single hospital, HCA South Tampa, with the same team every time, so the equipment and the routine stay consistent. A physician assistant he employs assists on every case and knows your specific procedure and recovery, so you’re not handed to a stranger afterward. His office medical assistants have been with him for over a decade. And patients can reach him directly after hours when something comes up. For a chronic condition, that kind of access changes how recovery feels.

Dr. Grandhige

Getting care from St. Petersburg

St. Petersburg patients don’t need a local gastroparesis clinic to get specialist care. The office is a short drive across the bay in South Tampa, reachable over the Gandy Bridge or the Howard Frankland. For a condition this specific, most people in Pinellas are closer to a dedicated foregut specialist than they realize.

The office is at 1315 South Howard Avenue, Suite 101, in South Tampa. It’s the yellow brick building next to Sally O’Neill’s Pizza, and parking is behind the restaurant.

The team is used to patients coming from across the bay and across the state, so trips get planned around your time. Where a test can be done closer to you in St. Pete, they’ll arrange that instead of making you drive over for it, and they group the remaining studies so you’re not crossing the bay again and again. If you already have prior records, endoscopy reports, or a past gastric emptying study, you can send them to info@tampareflux.com before your visit so Dr. Grandhige reviews everything first. Any procedure itself is performed at HCA South Tampa.

What patients and referring doctors say

The most common thing patients say is that they finally understood what was happening to them. Across reviews, the themes repeat: they felt heard, their prior tests and notes were actually read, and they weren’t pushed toward surgery. Patients often mention the diagrams Dr. Grandhige draws to explain how the stomach and pylorus work.

Referring physicians tell the same story from the other side. Gastroenterologists, ENT doctors, and primary care providers keep sending patients because those patients come back informed and reassured, whether or not a procedure was done. That referral pattern, built over 16 years in Tampa Bay, is the practice’s real track record.

Gastroparesis questions we hear most

In most people the cause is never found, which doctors call idiopathic gastroparesis. The most common known cause is diabetes, which can damage the vagus nerve that controls the stomach muscles. It can also follow surgery on the esophagus or stomach, certain cancer treatments, or medications like opioids that slow the gut.

With a four-hour gastric emptying study. You eat a light meal, usually eggs and toast or oatmeal, tagged with a small amount of radioactive material, and a scanner measures how much food is left in your stomach at set points over four hours. That is the test that confirms delayed emptying.

No. Treatment manages the condition rather than curing it. Diet, medication, and procedures like endoscopic pyloromyotomy work to reduce symptoms and keep you nourished. Many people do well long term, but gastroparesis is generally something you manage, not something that goes away.

No, and any surgeon who tells you otherwise is overselling it. It can improve how fast your stomach empties and cut nausea, bloating, and fullness by opening the pyloric muscle. Most patients still follow a modified diet afterward.

Someone whose gastric emptying study confirms delayed emptying, whose symptoms line up with that delay, and who hasn’t gotten enough relief from diet and medication. Dr. Grandhige confirms the cause with testing before recommending it, and he’ll say so if a procedure isn’t likely to help you.

An endoscopic pyloromyotomy opens the pyloric muscle through the mouth, with no incision and no implant. A gastric stimulator, used at some other centers, is a device placed in the body with a battery that needs replacing over time, and it’s generally reserved for diabetic or unexplained cases when medication hasn’t worked. They are different tools for different situations.

Yes. The office and any procedures are in South Tampa, a short drive across the bay from St. Petersburg. The team coordinates your testing to limit trips, arranges studies closer to you in St. Pete where possible, and reviews records you send ahead of your visit.

When nausea, bloating, vomiting, or feeling full after a few bites keeps interfering with eating and daily life, especially if medication and diet changes haven’t helped or you’re losing weight. Persistent or worsening symptoms are worth a specialist evaluation rather than more of the same.

You’ve probably spent long enough not knowing why eating feels like this

A gastric emptying study and an honest evaluation can tell you whether it’s gastroparesis, whether a procedure would help, and what to do if it wouldn’t.

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An endoscopy cannot tell you if you have reflux. It can only tell you if you have complications of GERD. 

If you are unhappy with your reflux symptoms, come in and we can discuss testing and treatments that can accurately diagnose your problem. 

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CALL US AT 813-922-2920
www.tampareflux.com

If you have a hiatal hernia and fit one of these categories, you should know your options. 

Dr. Grandhige is an expert in his field and performs 200 of these surgeries a year.  He is the only surgeon in the Tampa Bay Area who offers all surgical options - LINX, Fundoplications, TIF and will be one of 20 surgeons in America introducing the latest procedure RefluxStop in 2026. 

We accept most insurances but will verify yours before you come in.  These procedures are considered medically necessary and covered by your insurance.  You can expect to pay your in-network deductibles and nothing else. 

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What causes reflux ?

1.  Weak lower esophageal sphincter
2.  Hiatal hernia
3.  Flattening of the Angle of His
4.  Poor esophageal motility
5.  Gastroparesis (slow stomach)

NOT increased acid production

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If you are tired of avoiding your favorite foods or taking daily medications, we can help. 

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Call 813-922-2920 to schedule your appointment
All major insurances accepted.

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Not all patients need surgical intervention.  Many patients are living a heartburn free life with their PPIs. However 40% of patients taking PPIs are not getting the relief they need.  If you are one of those, you have options!  Come in and find out more. 
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