Gastroparesis Surgery In St. Petersburg, FL

When gastroparesis doesn’t respond to medication and diet changes, an endoscopic procedure called G-POEM can help the stomach empty by opening the pylorus, the muscular valve at the stomach’s outlet. Dr. Gopal Grandhige performs G-POEM at his foregut surgery practice in South Tampa, roughly 25 to 35 minutes from St. Petersburg, and he confirms with objective testing whether the procedure is likely to work before he recommends it. Many people who ask about surgery turn out not to be candidates. Sorting that out honestly, before an operation, is the whole job.

Gastroparesis surgery, in plain terms

Gastroparesis surgery targets one specific muscle: the pylorus. Gastroparesis means the stomach empties too slowly even though nothing is physically blocking it, which causes nausea, early fullness, bloating, and vomiting of food eaten hours earlier. According to the NIH’s NIDDK, diabetes is the most common known cause, though many cases are idiopathic (no identified cause) or follow surgery. When the pylorus fails to open normally, food backs up behind it. The pylorus-directed procedures loosen or divide that valve so the stomach drains more freely.

Two things are worth stating up front. First, these procedures manage symptoms; they do not reverse the underlying nerve or muscle problem. Second, they work best when slow emptying is driven by the pylorus, not by diffuse failure of the whole stomach muscle. That distinction is why testing matters more than symptoms alone. You can read a fuller overview of how the condition is diagnosed and treated on the practice gastroparesis page.

How G-POEM (per-oral pyloromyotomy) works

G-POEM is an incisionless procedure done entirely through the mouth. Using a flexible endoscope, the surgeon creates a small tunnel in the stomach lining near the pylorus, then divides the pyloric muscle with an endoscopic knife so the valve opens more easily. It’s also called POP (per-oral pyloromyotomy); the two names describe minor technical variations of the same operation. Because there are no abdominal incisions, there’s no abdominal-wall pain, and many patients go home within a day or two. Diet is advanced gradually over the following weeks while the area heals.

Dr. Grandhige is one of a small number of surgeons performing this endoscopic procedure in the Tampa Bay area, which is a large part of why patients cross the bay from Pinellas County for it.

What the success rates actually show

In pooled research, G-POEM brings meaningful symptom relief to about 72% of carefully selected patients one year out, and the surgeon completes the myotomy as intended in more than 98% of cases. Most pages skip these numbers, so here is the fuller picture. Across peer-reviewed meta-analyses, “clinical success” means a real drop in symptoms such as nausea and vomiting, not a flawless result. Benefits last for many people, with data showing durability out to about three years, though a share of patients see symptoms return over time. Serious complications are uncommon; the pooled adverse-event rate is roughly 8%, and most events are minor.

Odds also depend on the cause. A meta-analysis comparing etiologies reported clinical success around 70% for post-surgical gastroparesis, 65% for diabetic gastroparesis, and 60% for idiopathic cases. Patients whose main symptoms are nausea and vomiting tend to respond better than those whose main symptom is pain. Higher gastric retention on the emptying study, and an early response in the first month, also point toward a better outcome. The same research is blunt about the other side: used indiscriminately, without testing to find the right patients, G-POEM’s effectiveness drops. That is exactly why selection comes first here.

Happy patient after heartburn surgery

Who benefits, who doesn’t, and why testing comes first

Surgery is on the table only after objective testing confirms the diagnosis and points to the pylorus as the problem. Symptoms alone can’t diagnose gastroparesis, because several conditions mimic it. Dr. Grandhige relies on a gastric emptying study (the standard test, which tracks how fast a light, labeled meal leaves the stomach over four hours) and upper endoscopy, and he uses advanced tools such as EndoFLIP in his foregut practice to measure how a valve opens. If testing shows the slow emptying comes from diffuse stomach-muscle failure rather than the pylorus, an operation on the pylorus is unlikely to help, and he’ll say so.

Good candidates generally have refractory gastroparesis (symptoms that persist despite medication and diet), delayed emptying confirmed on testing, and nausea or vomiting as the dominant complaint. Poorer candidates include people whose symptoms are mainly pain, whose testing doesn’t confirm delayed emptying, or whose slow emptying isn’t pylorus-driven. Severe malnutrition changes the plan too, because nutrition often has to be stabilized before any definitive procedure is safe.

This is where the approach differs from a general surgeon who treats gastroparesis occasionally. Dr. Grandhige operates on fewer patients on purpose, because patients chosen carefully are far more likely to improve. Many people arrive expecting surgery and leave instead with a clear diagnosis, an explanation that finally makes sense, and a non-surgical plan.

Your surgical options for gastroparesis

G-POEM is the least invasive option, but it isn’t the only one, and the right choice depends on your anatomy and how severe the disease is.

Pyloroplasty, done robotically or laparoscopically through small abdominal incisions, divides and reshapes the pyloric muscle for a durable opening. It targets the same valve as G-POEM, through a surgical route rather than an endoscopic one.

For people with severe weight loss and malnutrition who aren’t yet safe candidates for a definitive procedure, a feeding tube can vent the stomach and deliver nutrition directly into the intestine. That stabilizes a person so other options can be considered later.

Subtotal gastrectomy, removal of most of the stomach, is reserved for rare, severe cases that don’t respond to anything else and are seriously affecting a person’s life. Gastric electrical stimulation is another approach used in the field for some diabetic and idiopathic patients; Dr. Grandhige’s own focus is the pylorus-directed procedures above. He treats other foregut conditions as well, including achalasia and reflux disease, so overlapping problems get handled together rather than piecemeal.

Getting to Dr. Grandhige from St. Petersburg

The office sits at 1315 South Howard Avenue, Suite 101, in Tampa’s Hyde Park (SoHo) district, about 25 to 35 minutes from central St. Petersburg depending on traffic and whether you cross on the Gandy or the Howard Frankland bridge. All procedures are performed at HCA South Tampa Hospital, a single facility Dr. Grandhige uses on purpose so the same anesthesia team, nurses, and surgical staff assist every case. He previously operated at Bayfront in St. Petersburg and at several other area hospitals; consolidating to one site is a deliberate choice for consistency and safety.

St. Petersburg and wider Pinellas County residents make up a regular share of the practice, and out-of-town logistics are routine here. When testing can be done closer to home, the office arranges that first so your trip across the bay is efficient. Gastroparesis often overlaps with severe acid reflux and other foregut conditions, and if you’re dealing with more than one problem, related issues like GERD or silent reflux can be evaluated in the same workup. Plain-language articles on these topics are on the practice blog.

About Dr. Gopal Grandhige

Dr. Grandhige is a board-certified general surgeon who has focused on foregut surgery (benign conditions of the esophagus, diaphragm, and stomach) in Tampa Bay since 2009. He earned his undergraduate degree at Johns Hopkins University and his medical degree at the University of Michigan, then completed general surgery residency and two fellowships at Yale-New Haven Hospital: one in foregut surgery and minimally invasive surgery, and one in burn and critical care. He is a Fellow of the American College of Surgeons (FACS), a member of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES), and a founding member of the American Foregut Society. More on his training and philosophy is on the About Us page.

His practice runs largely on referrals from gastroenterologists, ENT physicians, pulmonologists, and primary care doctors across Florida, in good part because patients come back well-informed whether or not they end up having surgery.

Dr. Grandhige pointing left

FAQS

No. G-POEM manages gastroparesis by opening the pylorus so the stomach empties better, which reduces symptoms like nausea and vomiting. It doesn’t reverse the underlying nerve or muscle problem, and symptoms can return over time for some people, so ongoing care still matters.

In published pooled data, about 72% of carefully selected patients have meaningful symptom relief one year after G-POEM, with benefits lasting out to roughly three years for many. Results vary by cause: around 70% for post-surgical, 65% for diabetic, and 60% for idiopathic gastroparesis. Nausea- and vomiting-predominant patients tend to respond better than pain-predominant ones.

Testing decides, not symptoms. A gastric emptying study and an upper endoscopy confirm whether emptying is truly delayed and whether the pylorus is the driver. If your slow emptying comes from diffuse stomach-muscle failure, or your main symptom is pain, the procedure is less likely to help, and Dr. Grandhige will tell you that directly.

The Tampa office is about 25 to 35 minutes from central St. Petersburg, depending on traffic and whether you cross on the Gandy or the Howard Frankland bridge. Procedures are performed at HCA South Tampa Hospital.

Because G-POEM is done through the mouth with no abdominal incisions, there’s no abdominal-wall pain and many patients go home within a day or two. You’ll follow a structured diet that starts with liquids and advances over the following weeks while the pylorus heals.

The main test is a gastric emptying study, which tracks how quickly a light, labeled meal leaves your stomach over four hours. An upper endoscopy checks the anatomy and rules out a blockage. Bringing prior records and test results to your visit speeds everything up.

Many people aren’t, and that’s a legitimate result. Dr. Grandhige will explain why, and depending on the cause, the plan may center on diet, medication, nutrition support, or referral to the right specialist. The goal is the correct treatment, not a procedure for its own sake.

Yes. He also performs robotic or laparoscopic pyloroplasty, and for severe cases he offers feeding tubes and, rarely, subtotal gastrectomy. The choice depends on your testing, your anatomy, and how the disease is affecting you.

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An endoscopy cannot tell you if you have reflux. It can only tell you if you have complications of GERD. 

If you are unhappy with your reflux symptoms, come in and we can discuss testing and treatments that can accurately diagnose your problem. 

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www.tampareflux.com

If you have a hiatal hernia and fit one of these categories, you should know your options. 

Dr. Grandhige is an expert in his field and performs 200 of these surgeries a year.  He is the only surgeon in the Tampa Bay Area who offers all surgical options - LINX, Fundoplications, TIF and will be one of 20 surgeons in America introducing the latest procedure RefluxStop in 2026. 

We accept most insurances but will verify yours before you come in.  These procedures are considered medically necessary and covered by your insurance.  You can expect to pay your in-network deductibles and nothing else. 

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What causes reflux ?

1.  Weak lower esophageal sphincter
2.  Hiatal hernia
3.  Flattening of the Angle of His
4.  Poor esophageal motility
5.  Gastroparesis (slow stomach)

NOT increased acid production

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Anyone can be victim to GERD and though weight loss can help reduce GERD symptoms. Many athletes with high impact workouts may continue to have these symptoms. This may be a symptom of a hiatal hernia or other issue. We are more then happy to assist you in finding your solution, just click the link below. 
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All major insurances accepted.

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Not all patients need surgical intervention.  Many patients are living a heartburn free life with their PPIs. However 40% of patients taking PPIs are not getting the relief they need.  If you are one of those, you have options!  Come in and find out more. 
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